Experimental Neurology Center (ZEN)

Research group leader

Research focuses

My current research is focused on understanding the brain dynamics that enable cognitive processing in health and disease.In specific, we use sleep as a window to understand how different brain nuclei and their specific cell types (neurons and astrocytes) modulate sleep, sleep oscillations and sleep-dependent cognitive processes in mouse models.Current research programs in my group are designed to link fundamental aspects of sleep brain oscillations with non-invasive therapeutic strategies to improve sleep disturbances and cognitive deficits in neurological (stroke) and psychiatric disorders.




Short description

Sleep and brain plasticity

Current therapeutical interventions to improve motor or cognitive recovery after stroke range from non- selective modulation of large brain areas to global physical rehabilitation. In this context, local low- frequency, high-amplitude oscillations in the peri-infarct zone share similarities with brain plasticity-promoting sleep slow waves (SW). Whether these support functional plasticity for local recovery of cortical function remains unclear.

Group Members 

  • Albert Lopez, Informatiker



Further information

Research group’s website